Invention Grant
US08211420B2 Interleukin-21 variants with altered binding to the IL-21 receptor
有权
具有改变的IL-21受体结合的白介素-21变体
- Patent Title: Interleukin-21 variants with altered binding to the IL-21 receptor
- Patent Title (中): 具有改变的IL-21受体结合的白介素-21变体
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Application No.: US12520057Application Date: 2007-12-20
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Publication No.: US08211420B2Publication Date: 2012-07-03
- Inventor: Kent Bondensgaard , Lishan Kang , Siv Annegrethe Hjorth , Dennis Madsen
- Applicant: Kent Bondensgaard , Lishan Kang , Siv Annegrethe Hjorth , Dennis Madsen
- Applicant Address: DK Bagsvaerd
- Assignee: Novo Nordisk A/S
- Current Assignee: Novo Nordisk A/S
- Current Assignee Address: DK Bagsvaerd
- Agency: Woodcock Washburn LLP
- Priority: EP06126901 20061221
- International Application: PCT/EP2007/064326 WO 20071220
- International Announcement: WO2008/074863 WO 20080626
- Main IPC: C07K14/435
- IPC: C07K14/435 ; A61K45/00
Abstract:
The invention is concerned with IL-21 polypeptide variants having an altered binding to the common gamma chain (c) of the IL-21 receptor and the use thereof in therapy.
Public/Granted literature
- US20100196309A1 INTERLEUKIN-21 VARIANTS WITH ALTERED BINDING TO THE IL-21 RECEPTOR Public/Granted day:2010-08-05
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