A composition for prevention digestive infection in a ruminant infant is disclosed. The composition consists of: a predetermined amount of yolk immunoglobulin (IgY) for a target bacteria; a predetermined amount of a plurality of hormones and a predetermined amount of a plurality of proteins, wherein said plurality of hormones comprises of a group consisting of bovine insulin (bIns), bovine growth hormone (bGH), and bovine prolactine (bPrl), and wherein said plurality of proteins comprises of a group consisting of, bovine insulin like growth factor (bIGF), lactoferrin factor (LF), and transferring factor (TF); and a predetermined amount of bacterial biomass, wherein said bacterial biomass comprises of a group consisting of bacterial DNA, bacterial RNA, bacterial protein, and bacterial polysaccharides.