Invention Grant
US08211442B2 Mucosal vaccine enabling switching from production of IgA antibody to production of both of IgA and IgG antibodies
有权
粘膜疫苗能够从IgA抗体的生产切换到IgA和IgG抗体两者的生产
- Patent Title: Mucosal vaccine enabling switching from production of IgA antibody to production of both of IgA and IgG antibodies
- Patent Title (中): 粘膜疫苗能够从IgA抗体的生产切换到IgA和IgG抗体两者的生产
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Application No.: US11990001Application Date: 2006-08-04
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Publication No.: US08211442B2Publication Date: 2012-07-03
- Inventor: Hiroshi Kido , Dai Mizuno
- Applicant: Hiroshi Kido , Dai Mizuno
- Applicant Address: JP Tokushima
- Assignee: The University of Tokushima
- Current Assignee: The University of Tokushima
- Current Assignee Address: JP Tokushima
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JP2005-227504 20050805
- International Application: PCT/JP2006/315515 WO 20060804
- International Announcement: WO2007/018152 WO 20070215
- Main IPC: A61K39/12
- IPC: A61K39/12

Abstract:
In the aim of practical utilization of a safe and effective transnasal/inactivated/mucosal vaccine and establishment of a technology for imparting capacity of producing both of IgA and IgG antibodies to a conventional inactivated vaccine, toxoid, allergen, or the like, a means for prevention and treatment of allergy, and the like, it is intended to provide an antigen-drug vehicle (AD vehicle) enabling transnasal, transmucosal, and transdermal administrations, an inactivated vaccine simultaneously inducing a mucosal immunity and humoral immunity by using the AD vehicle, a production method of the inactivated vaccine, an AD vehicle enabling a switch from induction of selective production of IgA antibody to induction of both of IgA and IgG antibodies, and a transnasal vaccine, a mucosal vaccine, a therapeutic/prophylactic agent for allergy, and the like using the AD vehicle.
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