Invention Grant
US08211638B2 Genetic polymorphisms associated with liver fibrosis, methods of detection and uses thereof
有权
与肝纤维化相关的遗传多态性，检测方法及其应用
- Patent Title: Genetic polymorphisms associated with liver fibrosis, methods of detection and uses thereof
- Patent Title (中): 与肝纤维化相关的遗传多态性，检测方法及其应用
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Application No.: US12769896Application Date: 2010-04-29
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Publication No.: US08211638B2Publication Date: 2012-07-03
- Inventor: Hongjin Huang , Ramasubbu Venkatesh , Michele Cargill
- Applicant: Hongjin Huang , Ramasubbu Venkatesh , Michele Cargill
- Applicant Address: US CA Alameda
- Assignee: Celera Corporation
- Current Assignee: Celera Corporation
- Current Assignee Address: US CA Alameda
- Agency: Celera Corporation
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34
Abstract:
The present invention is based on the discovery of genetic polymorphisms that are associated with liver fibrosis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
Public/Granted literature
- US20100216154A1 GENETIC POLYMORPHISMS ASSOCIATED WITH LIVER FIBROSIS, METHODS OF DETECTION AND USES THEREOF Public/Granted day:2010-08-26
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