Invention Grant
US08211683B2 Plasmid, transformants and process for production of 3- carboxymuconolactone
有权
质粒，转化体和生产3-羧基粘康酸内酯的方法
- Patent Title: Plasmid, transformants and process for production of 3- carboxymuconolactone
- Patent Title (中): 质粒，转化体和生产3-羧基粘康酸内酯的方法
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Application No.: US12310095Application Date: 2007-08-10
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Publication No.: US08211683B2Publication Date: 2012-07-03
- Inventor: Kohei Mase , Toshihisa Shimo , Naoki Ohara , Yoshihiro Katayama , Kiyotaka Shigehara , Eiji Masai , Masao Fukuda , Seiji Ohara , Masaya Nakamura , Yuichiro Otsuka
- Applicant: Kohei Mase , Toshihisa Shimo , Naoki Ohara , Yoshihiro Katayama , Kiyotaka Shigehara , Eiji Masai , Masao Fukuda , Seiji Ohara , Masaya Nakamura , Yuichiro Otsuka
- Applicant Address: JP Aichi-Ken JP Tokyo JP Niigata JP Ibaraki
- Assignee: Kabushiki Kaisha Toyota Jidoshokki,National University Corporation, Tokyo University of Agriculture and Technology,Nagoya University of Technology,Forestry and Forest Products Research Institute
- Current Assignee: Kabushiki Kaisha Toyota Jidoshokki,National University Corporation, Tokyo University of Agriculture and Technology,Nagoya University of Technology,Forestry and Forest Products Research Institute
- Current Assignee Address: JP Aichi-Ken JP Tokyo JP Niigata JP Ibaraki
- Agency: Locke Lord LLP
- Priority: JP2006-218524 20060810
- International Application: PCT/JP2007/065989 WO 20070810
- International Announcement: WO2008/018640 WO 20080214
- Main IPC: C12N9/00
- IPC: C12N9/00 ; C12N15/00 ; C12N1/20
Abstract:
There is provided a process for industrial production of simple 3-carboxy-cis,cis-muconic acid and/or 3-carboxymuconolactone from low molecular mixtures derived from plant components such as vanillin, vanillic acid and protocatechuic acid, via a multistage enzyme reaction. A recombinant plasmid containing a vanillate demethylase gene (vanAB genes), benzaldehyde dehydrogenase gene (ligV gene) and protocatechuate 3,4-dioxygenase gene (pcaHG genes); transformants incorporating the plasmid; and a process for production of 3-carboxy-cis,cis-muconic acid and/or 3-carboxymuconolactone characterized by culturing the transformants in the presence of vanillin, vanillic acid, protocatechuic acid or a mixture of two or more thereof.
Public/Granted literature
- US20100075388A1 PLASMID, TRANSFORMANTS AND PROCESS FOR PRODUCTION OF 3- CARBOXYMUCONOLACTONE Public/Granted day:2010-03-25
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