Invention Grant
US08211688B2 Process for producing L-glutamine using Escherichia coli with deficient glnB and glnE function
有权
使用具有缺失glnB和glnE功能的大肠杆菌生产L-谷氨酰胺的方法
- Patent Title: Process for producing L-glutamine using Escherichia coli with deficient glnB and glnE function
- Patent Title (中): 使用具有缺失glnB和glnE功能的大肠杆菌生产L-谷氨酰胺的方法
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Application No.: US11630396Application Date: 2005-06-24
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Publication No.: US08211688B2Publication Date: 2012-07-03
- Inventor: Shin-ichi Hashimoto , Kazuhiko Tabata
- Applicant: Shin-ichi Hashimoto , Kazuhiko Tabata
- Applicant Address: JP Toyko
- Assignee: Kyowa Hakko Bio Co., Ltd.
- Current Assignee: Kyowa Hakko Bio Co., Ltd.
- Current Assignee Address: JP Toyko
- Agency: Fitzpatrick, Cella, Harper & Scinto
- Priority: JP2004-189012 20040625
- International Application: PCT/JP2005/011637 WO 20050624
- International Announcement: WO2006/001380 WO 20060105
- Main IPC: C12P13/14
- IPC: C12P13/14 ; C12N1/20
Abstract:
The present invention provides a microorganism belonging to the genus Escherichia in which the activities of glutamine-synthetase adenylyltransferase (GlnE protein) and PII regulatory protein for glutamine synthetase are reduced or lost and which has the ability to form and accumulate L-glutamine or a substance biosynthesized utilizing nitrogen supplied by L-glutamine, and a process for producing L-glutamine or the substance biosynthesized utilizing nitrogen supplied by L-glutamine using the microorganism.
Public/Granted literature
- US20080038786A1 Method of Producing Substance Public/Granted day:2008-02-14
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