Invention Grant
- Patent Title: Induction of differential stress resistance and uses thereof
- Patent Title (中): 感应差压应力及其用途
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Application No.: US12058600Application Date: 2008-03-28
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Publication No.: US08211700B2Publication Date: 2012-07-03
- Inventor: Valter Longo
- Applicant: Valter Longo
- Applicant Address: US CA Los Angeles
- Assignee: University of Southern California
- Current Assignee: University of Southern California
- Current Assignee Address: US CA Los Angeles
- Agency: Brooks Kushman P.C.
- Main IPC: C12Q1/00
- IPC: C12Q1/00 ; C12N5/00 ; C12N5/02 ; C12N5/06 ; C12N5/08 ; C12N5/10 ; G01N33/48
Abstract:
This invention relates to methods of inducing differential stress resistance in a subject with cancer by starving the subject for a short term, administering a cell growth inhibitor to the subject, or reducing the caloric or glucose intake by the subject. The induced differential stress resistance results in improved resistance to cytotoxicity in normal cells, which, in turn, reduces cytotoxic side-effects due to chemotherapy, as well as improved effectiveness of chemotherapeutic agents.
Public/Granted literature
- US20080242638A1 INDUCTION OF DIFFERENTIAL STRESS RESISTANCE AND USES THEREOF Public/Granted day:2008-10-02
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