Invention Grant
US08211852B2 Molecules and methods of using same for treating CCR5/CCR5 ligands associated diseases
有权
分子和使用它们的方法来治疗CCR5 / CCR5配体相关疾病
- Patent Title: Molecules and methods of using same for treating CCR5/CCR5 ligands associated diseases
- Patent Title (中): 分子和使用它们的方法来治疗CCR5 / CCR5配体相关疾病
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Application No.: US12224053Application Date: 2007-02-18
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Publication No.: US08211852B2Publication Date: 2012-07-03
- Inventor: Nathan Karin , Gizi Wildbaum
- Applicant: Nathan Karin , Gizi Wildbaum
- Applicant Address: IL Haifa
- Assignee: Rappaport Family Institute for Research in the Medical Sciences
- Current Assignee: Rappaport Family Institute for Research in the Medical Sciences
- Current Assignee Address: IL Haifa
- Agency: Cooper & Dunham LLP
- Agent John P. White
- International Application: PCT/IL2007/000219 WO 20070218
- International Announcement: WO2007/094005 WO 20070823
- Main IPC: A61K38/19
- IPC: A61K38/19 ; C07H21/00 ; C07K14/52
Abstract:
Soluble molecules are provided. Thus, for example, provided is a soluble molecule which comprises a heterologous amino acid sequence conjugated to a CCR5 amino acid sequence being capable of binding a CCR5 ligand, and wherein the molecule is devoid of an N-terminus domain of CCR5. Also provided are pharmaceutical compositions which comprise the above molecules and methods and uses of same.
Public/Granted literature
- US20100227805A1 Molecules and Methods of Using Same for Treating CCR5/CCR5 Ligands Associated Diseases Public/Granted day:2010-09-09
Information query
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