Invention Grant
US08211853B2 Method of promoting apoptosis of differentiated adipocytes and increasing endogenous expression of SFRP-5 peptide by administration of SFRP-5 peptide
有权
通过施用SFRP-5肽促进分化的脂肪细胞凋亡和增加SFRP-5肽的内源性表达的方法
- Patent Title: Method of promoting apoptosis of differentiated adipocytes and increasing endogenous expression of SFRP-5 peptide by administration of SFRP-5 peptide
- Patent Title (中): 通过施用SFRP-5肽促进分化的脂肪细胞凋亡和增加SFRP-5肽的内源性表达的方法
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Application No.: US12803963Application Date: 2010-07-09
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Publication No.: US08211853B2Publication Date: 2012-07-03
- Inventor: Kiran K. Chada , Roland Chouinard , Hena Ashar , Md. Abu Sayed
- Applicant: Kiran K. Chada , Roland Chouinard , Hena Ashar , Md. Abu Sayed
- Applicant Address: US NJ Piscataway
- Assignee: HMGene Inc.
- Current Assignee: HMGene Inc.
- Current Assignee Address: US NJ Piscataway
- Agency: Cooper & Dunham LLP
- Agent Gary J. Gershik
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61P3/06
Abstract:
Disclosed is a method of reducing the amount of adipose tissue in a subject comprising administering to the subject an amount of an sFRP-5 peptide effective to reduce the amount of adipose tissue, or an amount of a molecule effective to stimulate expression of the sFRP-5 peptide in the subject. Also disclosed is a screen for molecules that can reduce the amount of adipose tissue in a subject.
Public/Granted literature
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