Invention Grant
US08211864B2 Compositions and methods for the intracellular disruption of VEGF and VEGFR-2 by intraceptors
有权
VEGF和VEGFR-2细胞内破坏的组成和方法
- Patent Title: Compositions and methods for the intracellular disruption of VEGF and VEGFR-2 by intraceptors
- Patent Title (中): VEGF和VEGFR-2细胞内破坏的组成和方法
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Application No.: US11814890Application Date: 2006-01-26
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Publication No.: US08211864B2Publication Date: 2012-07-03
- Inventor: Balamurali Ambati , Nirbhai Singh , Shivan Amin
- Applicant: Balamurali Ambati , Nirbhai Singh , Shivan Amin
- Applicant Address: US GA Atlanta US UT Salt Lake City
- Assignee: Medical College of Georgia Research Institute,University of Utah Research Foundation
- Current Assignee: Medical College of Georgia Research Institute,University of Utah Research Foundation
- Current Assignee Address: US GA Atlanta US UT Salt Lake City
- Agency: Thorpe North & Western LLP
- International Application: PCT/US2006/002684 WO 20060126
- International Announcement: WO2006/081311 WO 20060803
- Main IPC: A61K31/70
- IPC: A61K31/70 ; C12N15/00 ; C07H21/04
Abstract:
The present invention provides an intraceptor that interacts with and decreases activity of with VEGF and/or a VEGFR for the treatment of angiogenesis-related conditions. The present invention further provides pharmaceutical compositions, and methods of use thereof, for the treatment and prevention of an angiogenesis-related condition using said intraceptors. The invention further provides for nucleic acids encoding said intraceptors.
Public/Granted literature
- US20080318857A1 Compositions and Methods for the Intracellular Disruption of Vegf and Vegfr-2 By Intraceptors Public/Granted day:2008-12-25
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