Invention Grant
- Patent Title: Inhibitors of diacylglycerol acyltransferase
- Patent Title (中): 二酰基甘油酰基转移酶抑制剂
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Application No.: US12638244Application Date: 2009-12-15
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Publication No.: US08211914B2Publication Date: 2012-07-03
- Inventor: David Robert Bolin , Adrian Wai-Hing Cheung , Fariborz Firooznia , Nicholas Marcopulos , Yimin Qian
- Applicant: David Robert Bolin , Adrian Wai-Hing Cheung , Fariborz Firooznia , Nicholas Marcopulos , Yimin Qian
- Applicant Address: US PA Fort Washington
- Assignee: Madrigal Pharmaceuticals, Inc.
- Current Assignee: Madrigal Pharmaceuticals, Inc.
- Current Assignee Address: US PA Fort Washington
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- Agent Ivor R. Elrifi; Heidi A. Erlacher
- Main IPC: A61K31/445
- IPC: A61K31/445 ; C07D413/12

Abstract:
Provided herein are amides containing at least a four ring structure, which are inhibitors of diacylglycerol acyltransferase and are useful for the treatment of diseases such as, for example, obesity, type II diabetes mellitus and metabolic syndrome.
Public/Granted literature
- US20100152445A1 Inhibitors of Diacylglycerol Acyltransferase Public/Granted day:2010-06-17
Information query
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