Invention Grant
US08211918B2 Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators
有权
5-氨基-4,6-二取代吲哚和5-氨基-4,6-二取代二氢吲哚的衍生物作为钾通道调节剂
- Patent Title: Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators
- Patent Title (中): 5-氨基-4,6-二取代吲哚和5-氨基-4,6-二取代二氢吲哚的衍生物作为钾通道调节剂
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Application No.: US12856514Application Date: 2010-08-13
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Publication No.: US08211918B2Publication Date: 2012-07-03
- Inventor: Jean-Michel Vernier , Huanming Chen , Jianlan Song
- Applicant: Jean-Michel Vernier , Huanming Chen , Jianlan Song
- Applicant Address: US CA Aliso Viejo
- Assignee: Valeant Pharmaceuticals International
- Current Assignee: Valeant Pharmaceuticals International
- Current Assignee Address: US CA Aliso Viejo
- Agency: Jones Day
- Main IPC: A61K31/4439
- IPC: A61K31/4439 ; A61K31/404 ; C07D401/06 ; C07D209/22
Abstract:
This invention provides compounds of formula I where the dashed line represents an optional double bond; where R1 is phenyl, naphthyl, pyridyl, pyrimidyl, pyrrolyl, imidazolyl, pyrazyl, furyl, thienyl, oxazolyl, isoxazolyl, thiazolyl, or isothiazolyl, optionally substituted, and other substituents are defined herein. Such compounds are potassium channel modulators.
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