Invention Grant
US08212021B2 Process for making 5-azacytosine nucleosides and their derivatives
有权
制备5-氮胞嘧啶核苷及其衍生物的方法
- Patent Title: Process for making 5-azacytosine nucleosides and their derivatives
- Patent Title (中): 制备5-氮胞嘧啶核苷及其衍生物的方法
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Application No.: US12538271Application Date: 2009-08-10
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Publication No.: US08212021B2Publication Date: 2012-07-03
- Inventor: Julian Paul Henschke , Xiaoheng Zhang , Lunghu Wang , Yung Fa Chen
- Applicant: Julian Paul Henschke , Xiaoheng Zhang , Lunghu Wang , Yung Fa Chen
- Applicant Address: TW Tainan
- Assignee: ScinoPharm Taiwan, Ltd.
- Current Assignee: ScinoPharm Taiwan, Ltd.
- Current Assignee Address: TW Tainan
- Main IPC: C07H19/12
- IPC: C07H19/12
Abstract:
A process of synthesizing a 5-azacytosine nucleoside, such as azacitidine and decitabine, comprises coupling a silylated 5-azacytosine with a protected D-ribofuranose of formula in the presence of a sulfonic acid catalyst.
Public/Granted literature
- US20100036112A1 Process for Making 5-Azacytosine Nucleosides and Their Derivatives Public/Granted day:2010-02-11
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