Invention Grant
- Patent Title: sEH inhibitors and their use
- Patent Title (中): sEH抑制剂及其用途
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Application No.: US12757089Application Date: 2010-04-09
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Publication No.: US08212032B2Publication Date: 2012-07-03
- Inventor: Yun Ding , Reema K. Thalji , Joseph P. Marino, Jr.
- Applicant: Yun Ding , Reema K. Thalji , Joseph P. Marino, Jr.
- Applicant Address: US PA Philadelphia
- Assignee: GlaxoSmithKline LLC.
- Current Assignee: GlaxoSmithKline LLC.
- Current Assignee Address: US PA Philadelphia
- Agent Linda E. Hall; John L. Lemanowicz
- Main IPC: C07D251/50
- IPC: C07D251/50 ; A61K31/53 ; A61P9/08 ; A61P9/10 ; A61P9/12 ; A61P11/06 ; A61P11/00 ; A61P13/12
Abstract:
The invention is directed to novel sEH inhibitors and their use in the treatment of diseases mediated by the sEH enzyme. Specifically, the invention is directed to (Cis)-N-{[4-cyano-2-(trifluoromethyl)phenyl]methyl}-3-{[4-methyl-6-(methylamino)-1,3,5-triazin-2-yl]amino}cyclohexanecarboxamide; or a pharmaceutically acceptable salt thereof, and N-{[4-cyano-2-(trifluoromethyl)phenyl]methyl}-3-{[4-methyl-6-(methylamino)-1,3,5-triazin-2-yl]amino}cyclohexanecarboxamide; or a pharmaceutically acceptable salt thereof.
Public/Granted literature
- US20100249137A1 Novel sEH Inhibitors and Their Use Public/Granted day:2010-09-30
Information query
