Invention Grant
US08212052B2 Dual-acting benzoimidazole antihypertensive agents 有权
双效苯并咪唑抗高血压药

Dual-acting benzoimidazole antihypertensive agents
Abstract:
The invention relates to compounds having the formula: wherein Ar, r, n, X, R2, R2′, R3, and R5-7 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have AT1 receptor antagonist activity and neprilysin inhibition activity. The invention also relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and a process and intermediates for preparing such compounds.
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