An arrangement is disclosed for offset compensation of a time-interleaved analog-to-digital converter, having a plurality of computing channels and being adapted to convert a signal from an analog domain to a digital domain. The arrangement comprises the time-interleaved analog-to-digital converter, an analog offset estimation and compensation unit adapted to estimate a mean offset for the plurality of computing channels, a digital offset estimation and compensation unit adapted to estimate a residual computing channel specific offset for each of the plurality of computing channels, and offset compensation means. The offset compensation means are adapted to perform offset compensation in the analog domain of each of the plurality of channels based on the estimated mean offset in the analog domain, and to perform offset compensation in the digital domain of each of the plurality of channels based on respective residual computing channel specific offset.