Systems and methods for IP communication over a distributed antenna system transport are provided. In one embodiment, a method for providing Ethernet connectivity over a distributed antenna system comprises receiving internet protocol (IP) formatted data from an internet protocol device coupled to a remote unit of a distributed antenna system; sampling wireless radio frequency (RF) signals received at the remote unit to produce digitized RF samples; generating a serial data stream for output to a host unit of the distributed antenna system, the serial data stream further comprising a multiple-timeslot communication frame providing a first partition of bandwidth for transporting the digitized RF samples and a second partition of bandwidth for implementing an Ethernet pipe for transporting the IP formatted data.