Systems, methods, and graphical user interfaces are provided for identifying, analyzing, and adopting opportunities for optimizing clinical processes within clinical facilities. An optimized practice process model may be defined for a particular clinical procedure, setting forth an optimal clinical process. In addition, critical levers may be identified within the optimal clinical process, representing the activities that have the greatest impact on outcomes. Clinical facilities may collect current measures for the critical levers, and the current measures may be compared against an optimal, benchmark, and/or target measure. Based on the comparison, opportunities for clinical process optimization may be identified. Those opportunities may then be analyzed and prioritized for adoption into a facility's current practice. Clinical processes within healthcare facilities may be further improved by continuously monitoring facility data and identifying further opportunities of optimization. Further, collected data may be used to refine the optimized practice process model, allowing for further optimization.