A system and method for enabling software applications as a service in a non-intrusive manner in isolated user groups (IUGs) is disclosed. In one embodiment, a method includes receiving a user request from one of the plurality of IUGs to access application functionality of one of plurality of software applications, identifying the one of the plurality of IUGs, locating one of the plurality of service modules by a service gateway based on a request sent by one of the plurality of service adapters, providing an appropriate access to the one of the plurality of IUGs, obtaining configuration data associated with the one of the plurality of IUGs, forwarding the configuration data and the user request to the one of the plurality of software applications, and generating an appropriate response associated with the application functionality and returning the generated appropriate response to the one of the plurality of IUGs.