Invention Grant
- Patent Title: HBV vaccine and a process of preparing the same
- Patent Title (中): HBV疫苗及其制备方法
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Application No.: US12225341Application Date: 2008-01-28
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Publication No.: US08216589B2Publication Date: 2012-07-10
- Inventor: Jung Sun Yum , Byung Cheol Ahn , Hyun Jin Jo , Dong Yeon Kim , Joo Youn Lee , Ki Hyun Kim , Jae Seung Yoon , Hong Mo Moon
- Applicant: Jung Sun Yum , Byung Cheol Ahn , Hyun Jin Jo , Dong Yeon Kim , Joo Youn Lee , Ki Hyun Kim , Jae Seung Yoon , Hong Mo Moon
- Applicant Address: KR Seongnam-si
- Assignee: Dobeel Corporation
- Current Assignee: Dobeel Corporation
- Current Assignee Address: KR Seongnam-si
- Agency: Vorys, Sater, Seymour and Pease LLP
- Agent Mih Suhn Koh
- Priority: KR10-2007-0010167 20070131
- International Application: PCT/KR2008/000518 WO 20080128
- International Announcement: WO2008/093976 WO 20080807
- Main IPC: A61K39/29
- IPC: A61K39/29 ; C12N15/09 ; C12N5/10 ; C12N1/21 ; C12N15/63
Abstract:
The present invention relates to an HBV vaccine comprising an entire hepatitis B surface antigen of L protein, M protein and S protein, in which the produced antigens form virus-like particles, and a multi-antigen vaccine further comprising an HBV core antigen in addition to the entire surface antigen, and a method for preparing the same. The vaccines provide various epitopes and have excellent immunogenicity to induce a strong humoral immune response as well as a cell-mediated immune response.
Public/Granted literature
- US20110165194A1 HBV Vaccine and a Process of Preparing the Same Public/Granted day:2011-07-07
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