Invention Grant
- Patent Title: Extracellular serine protease
- Patent Title (中): 细胞外丝氨酸蛋白酶
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Application No.: US12802335Application Date: 2010-06-04
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Publication No.: US08216794B2Publication Date: 2012-07-10
- Inventor: Timothy J. O'Brien , Lowell J. Underwood , John Beard , Kazushi Shigemasa
- Applicant: Timothy J. O'Brien , Lowell J. Underwood , John Beard , Kazushi Shigemasa
- Applicant Address: US AR Little Rock
- Assignee: Board of Trustees of the University of Arkansas
- Current Assignee: Board of Trustees of the University of Arkansas
- Current Assignee Address: US AR Little Rock
- Agent Benjamin Aaron Adler
- Main IPC: G01N33/53
- IPC: G01N33/53 ; G01N33/537 ; G01N33/50 ; C12P19/34 ; C07K16/18 ; C07K16/40
Abstract:
The present invention provides a DNA encoding a novel extracellular serine protease termed Tumor Antigen Derived Gene-14 (TADG-14) which is overexpressed in ovarian, breast and colon carcinoma samples. Also provided are vector and host cells capable of expressing the DNA of the present invention, as well as the uses of the DNA and protein of the present invention. Also provided is a TADG-14 protein variant that has a potential role for detecting and targeting of ovarian carcinomas.
Public/Granted literature
- US20100291124A1 Extracellular serine protease Public/Granted day:2010-11-18
Information query
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