Invention Grant
- Patent Title: Peptides for targeting apoptotic cells and uses thereof
- Patent Title (中): 用于靶向凋亡细胞的肽及其用途
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Application No.: US12465007Application Date: 2009-05-13
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Publication No.: US08217012B2Publication Date: 2012-07-10
- Inventor: Byung Heon Lee , In San Kim
- Applicant: Byung Heon Lee , In San Kim
- Applicant Address: KR Daegu
- Assignee: Kyungpook National University Industry-Academic Cooperation Foundation
- Current Assignee: Kyungpook National University Industry-Academic Cooperation Foundation
- Current Assignee Address: KR Daegu
- Agency: Edwards Wildman Palmer LLP
- Priority: KR10-2008-0044410 20080514
- Main IPC: A61K38/08
- IPC: A61K38/08 ; A61K49/00 ; A61K51/00 ; C07K7/06

Abstract:
A peptide capable of specifically targeting apoptotic cells undergoing apoptosis and a use thereof is described. Peptides having an amino acid sequence represented by any one of SEQ ID NO: 1 to SEQ ID NO: 12 targeted apoptotic cell. Uses for compositions comprising the peptides include detection of apoptotic cells drug delivery and imaging. The peptide of the present invention effectively detects apoptosis which is involved in tissues of neoplastic disease, myocardial infarction, stroke and arteriosclerosis. Accordingly, the peptide of the present invention may be bound to an imaging or treatment reagent to be used in diagnosis of diseases, imaging of drug reactions, and treatment for diseases by selective drug delivery.
Public/Granted literature
- US20090285754A1 PEPTIDES FOR TARGETING APOPTOTIC CELLS AND USES THEREOF Public/Granted day:2009-11-19
Information query
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