Invention Grant
- Patent Title: Heteroaryl derivatives
- Patent Title (中): 杂芳基衍生物
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Application No.: US12593566Application Date: 2008-03-28
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Publication No.: US08217031B2Publication Date: 2012-07-10
- Inventor: Masato Matsuoka , Tatsuya Oyama
- Applicant: Masato Matsuoka , Tatsuya Oyama
- Applicant Address: JP Kyoto
- Assignee: Nippon Shinyaku Co., Ltd.
- Current Assignee: Nippon Shinyaku Co., Ltd.
- Current Assignee Address: JP Kyoto
- Agency: McDermott Will & Emery LLP
- Priority: JP2007-094548 20070330; JP2007-146039 20070531
- International Application: PCT/JP2008/056217 WO 20080328
- International Announcement: WO2008/120761 WO 20081009
- Main IPC: A61K31/55
- IPC: A61K31/55 ; C07D223/16

Abstract:
The present invention relates to a compound represented by formula [1] or a pharmaceutically acceptable salt thereof: In formula [1], one of X and Y is CH and the other is oxygen or sulfur; R is hydrogen, etc.; Z is hydrogen, etc.; Ar is phenyl, etc.; and n is 1 or 2 and or m is 1 or 2, excluding compounds where n is 2 and m is 2 simultaneously. Also provided is a pharmaceutical composition comprising a compound of formula [1] or a pharmaceutically acceptable salt thereof as an active ingredient. The composition is usable as an agent for the prevention or treatment of depression, panic disorder, anxiety, obsessive-compulsive disorder, chronic pain, fibromyalgia, obesity, stress urinary incontinence, and overactive bladder.
Public/Granted literature
- US20100048537A1 HETEROARYL DERIVATIVES Public/Granted day:2010-02-25
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