Invention Grant
US08217070B2 2-substituted-1H-benzimidazole-4-carboxamides are PARP inhibitors
有权
2-取代-1H-苯并咪唑-4-甲酰胺是PARP抑制剂
- Patent Title: 2-substituted-1H-benzimidazole-4-carboxamides are PARP inhibitors
- Patent Title (中): 2-取代-1H-苯并咪唑-4-甲酰胺是PARP抑制剂
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Application No.: US12765293Application Date: 2010-04-22
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Publication No.: US08217070B2Publication Date: 2012-07-10
- Inventor: Gui-Dong Zhu , Virajkumar B. Gandhi , Jianchun Gong , Thomas D. Penning , Vincent L. Giranda , Sheela Thomas
- Applicant: Gui-Dong Zhu , Virajkumar B. Gandhi , Jianchun Gong , Thomas D. Penning , Vincent L. Giranda , Sheela Thomas
- Applicant Address: US IL Abbott Park
- Assignee: Abbott Laboratories
- Current Assignee: Abbott Laboratories
- Current Assignee Address: US IL Abbott Park
- Agent Susan L. Steele
- Main IPC: A61K31/4184
- IPC: A61K31/4184 ; C07D235/04
Abstract:
Compounds of Formula (I) inhibit the PARP enzyme and are useful for treating a disease or a disorder associated with PARP. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I), methods of treatment comprising compounds of Formula (I), and methods of inhibiting the PARP enzyme comprising compounds of Formula (I).
Public/Granted literature
- US20100234425A1 2-SUBSTITUTED-1H-BENZIMIDAZOLE-4-CARBOXAMIDES ARE PARP INHIBITORS Public/Granted day:2010-09-16
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