Invention Grant
- Patent Title: Anti-PD-L1 antibodies, compositions and articles of manufacture
- Patent Title (中): 抗PD-L1抗体，组合物和制品
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Application No.: US12633339Application Date: 2009-12-08
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Publication No.: US08217149B2Publication Date: 2012-07-10
- Inventor: Bryan Irving , Henry Chiu , Heather Maecker , Sanjeev Mariathasan , Sophie M. Lehar , Yan Wu , Jeanne Cheung
- Applicant: Bryan Irving , Henry Chiu , Heather Maecker , Sanjeev Mariathasan , Sophie M. Lehar , Yan Wu , Jeanne Cheung
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agent Craig G. Svoboda
- Main IPC: C07K16/00
- IPC: C07K16/00
Abstract:
The present application relates to anti-PD-L1 antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use enhance T-cell function to upregulate cell-mediated immune responses and for the treatment of T cell dysfunctional disorders, including infection (e.g., acute and chronic) and tumor immunity.
Public/Granted literature
- US20100203056A1 ANTI-PD-L1 ANTIBODIES AND THEIR USE TO ENHANCE T-CELL FUNCTION Public/Granted day:2010-08-12
Information query
