Invention Grant
US08217163B2 Application of highly conserved domain sequences from viral genome as template to design therapeutic slirnas
有权
将来自病毒基因组的高度保守的结构域序列应用于模板，设计治疗性疾病
- Patent Title: Application of highly conserved domain sequences from viral genome as template to design therapeutic slirnas
- Patent Title (中): 将来自病毒基因组的高度保守的结构域序列应用于模板，设计治疗性疾病
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Application No.: US12886446Application Date: 2010-09-20
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Publication No.: US08217163B2Publication Date: 2012-07-10
- Inventor: York Yuan Yuan Zhu , Li Chen , TieJun Li , YiXiang Lu , YunCheng Sun , Jinkang Wang
- Applicant: York Yuan Yuan Zhu , Li Chen , TieJun Li , YiXiang Lu , YunCheng Sun , Jinkang Wang
- Applicant Address: CN Nantong
- Assignee: Biomics Biotechnologies Co., Ltd.
- Current Assignee: Biomics Biotechnologies Co., Ltd.
- Current Assignee Address: CN Nantong
- Agency: Wilson Sonsini Goodrich & Rosati
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; C12Q1/68 ; A61K31/70
Abstract:
This invention relates to the application of the highly conserved sequences of viral genome, especially from a highly conserved domain of enteroviral genome as templates to design target small ligand RNAs (sliRNAs). The resulting sliRNAs are therapeutically active ingredients in the treatment of the related diseases caused by pathological angiogenesis.
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