Invention Grant
- Patent Title: Chromenone potassium channel blockers and uses thereof
- Patent Title (中): 色酮酮钾通道阻滞剂及其用途
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Application No.: US12442790Application Date: 2007-10-04
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Publication No.: US08217189B2Publication Date: 2012-07-10
- Inventor: Bernard Luke Flynn , Jonathan B. Baell , Andrew J. Harvey , Jason Hugh Chaplin , Dharam Paul , Jorgen Alvar Mould
- Applicant: Bernard Luke Flynn , Jonathan B. Baell , Andrew J. Harvey , Jason Hugh Chaplin , Dharam Paul , Jorgen Alvar Mould
- Applicant Address: AU Thebarton, South Australia
- Assignee: Bionomics Limited
- Current Assignee: Bionomics Limited
- Current Assignee Address: AU Thebarton, South Australia
- Agency: Scully, Scott, Murphy & Presser, P.C.
- International Application: PCT/AU2007/001476 WO 20071004
- International Announcement: WO2008/040058 WO 20080410
- Main IPC: C07D493/04
- IPC: C07D493/04 ; A61K31/35
Abstract:
The present invention relates to compounds useful in the modulation of potassium channel activity in cells, in particular the activity of Kv1.3 channels found in T cells. The invention also relates to the use of these compounds in the treatment or prevention of autoimmune and inflammatory diseases, including multiple sclerosis, pharmaceutical compositions containing these compounds and methods for their preparation.
Public/Granted literature
- US20090298931A1 NOVEL CHROMENONE POTASSIUM CHANNEL BLOCKERS AND USES THEREOF Public/Granted day:2009-12-03
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