An analog-to-digital converter timing circuit disclosed herein uses a clock generation circuit that makes the analog-to-digital converter insensitive to input clock duty cycle. Minimum clock jitter is added to the clock signal while propagating through the disclosed circuit. A method and system are also disclosed to clock an interleaved pipelined ADC such that the operation is insensitive to input clock duty cycle and such that the clock jitter on the sampling clock edges is minimized.