Invention Grant
US08221751B2 Tumor-targeting monoclonal antibodies to FZD10 and uses thereof
有权
针对FZD10的肿瘤靶向单克隆抗体及其用途
- Patent Title: Tumor-targeting monoclonal antibodies to FZD10 and uses thereof
- Patent Title (中): 针对FZD10的肿瘤靶向单克隆抗体及其用途
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Application No.: US12308095Application Date: 2006-08-24
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Publication No.: US08221751B2Publication Date: 2012-07-17
- Inventor: Yusuke Nakamura , Toyomasa Katagiri , Shuichi Nakatsuru , Keigo Endo , Motoki Kuhara , Kasumi Yagi
- Applicant: Yusuke Nakamura , Toyomasa Katagiri , Shuichi Nakatsuru , Keigo Endo , Motoki Kuhara , Kasumi Yagi
- Applicant Address: JP Kawasaki-Shi
- Assignee: Oncotherapy Science, Inc.
- Current Assignee: Oncotherapy Science, Inc.
- Current Assignee Address: JP Kawasaki-Shi
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- International Application: PCT/JP2006/317155 WO 20060824
- International Announcement: WO2007/148417 WO 20071227
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K51/10 ; C07K16/00 ; C12N5/16 ; C12N5/18 ; G01N33/53
Abstract:
The present invention relates to an antibody or a fragment thereof which is capable of binding to a Frizzled homologue 10 (FZD10) protein, such as a mouse monoclonal antibody, a chimeric antibody and a humanized antibody. Also, the present invention relates to a method for treating and/or preventing FZD10-associated disease; a method for diagnosis or prognosis of FZD10-associated disease; and a method for in vivo imaging of FZD10 in a subject.
Public/Granted literature
- US20110044896A1 Tumor-targeting monoclonal antibodies to FZD10 and uses thereof Public/Granted day:2011-02-24
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