Invention Grant
- Patent Title: Antibodies against human interleukin-13 and uses therefor
- Patent Title (中): 针对人白细胞介素-13的抗体并用于其
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Application No.: US12575896Application Date: 2009-10-08
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Publication No.: US08221752B2Publication Date: 2012-07-17
- Inventor: Marion T. Kasaian , Lioudmila Gennadievna Tchistiakova , Geertruida Machteld Veldman , Kimberly Ann Marquette , Xiang-Yang Tan , Debra D. Donaldson , Laura Long Lin , Tania Shane , Amy Sze Pui Tam , Eric Feyfant , Nancy L. Wood , Lori J. Fitz , Angela M. Widom , Kevin D. Parris , Samuel J. Goldman , Jose W. Saldanha
- Applicant: Marion T. Kasaian , Lioudmila Gennadievna Tchistiakova , Geertruida Machteld Veldman , Kimberly Ann Marquette , Xiang-Yang Tan , Debra D. Donaldson , Laura Long Lin , Tania Shane , Amy Sze Pui Tam , Eric Feyfant , Nancy L. Wood , Lori J. Fitz , Angela M. Widom , Kevin D. Parris , Samuel J. Goldman , Jose W. Saldanha
- Applicant Address: US NJ Madison
- Assignee: Wyeth LLC
- Current Assignee: Wyeth LLC
- Current Assignee Address: US NJ Madison
- Main IPC: A61K39/395
- IPC: A61K39/395

Abstract:
This application relates to antibodies, e.g., humanized antibodies, and antigen-binding fragments thereof, that bind to interleukin-13 (IL-13), in particular, human IL-13, and their uses in regulating immune responses mediated by IL-13. The antibodies disclosed herein are useful in diagnosing, preventing, and/or treating a subject, e.g., a human patient, one or more IL-13-associated disorders, e.g., respiratory disorders (e.g., asthma); atopic disorders (e.g., allergic rhinitis); inflammatory and/or autoimmune conditions of the skin (e.g., atopic dermatitis), and gastrointestinal organs (e.g., inflammatory bowel diseases (IBD)), as well as fibrotic and cancerous disorders.
Public/Granted literature
- US20100129360A1 ANTIBODIES AGAINST HUMAN INTERLEUKIN-13 AND USES THEREFOR Public/Granted day:2010-05-27
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