Invention Grant
- Patent Title: Neutralizing monoclonal antibodies to respiratory syncytial virus
- Patent Title (中): 呼吸道合胞病毒的中和单克隆抗体
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Application No.: US13250357Application Date: 2011-09-30
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Publication No.: US08221759B2Publication Date: 2012-07-17
- Inventor: Glenn R. Pilkington , Page S. Gilmour , Robert M. Chanock , James E. Crowe, Jr. , Brian R. Murphy
- Applicant: Glenn R. Pilkington , Page S. Gilmour , Robert M. Chanock , James E. Crowe, Jr. , Brian R. Murphy
- Applicant Address: US MD Frederick
- Assignee: Intracel Resources LLC
- Current Assignee: Intracel Resources LLC
- Current Assignee Address: US MD Frederick
- Agency: Dickstein Shapiro LLP
- Main IPC: A61K39/42
- IPC: A61K39/42

Abstract:
The present invention relates to the identification and cloning of a novel neutralizing human monoclonal antibody to the Respiratory Syncytial Virus. The invention provides such antibodies, fragments of such antibodies retaining RSV-binding ability, chimeric antibodies retaining RSV-binding ability, and pharmaceutical compositions including such antibodies. The invention further provides for isolated nucleic acids encoding the antibodies of the invention and host cells transformed therewith. Finally, the invention provides for diagnostic and therapeutic methods employing the antibodies and nucleic acids of the invention.
Public/Granted literature
- US20120087909A1 NEUTRALIZING MONOCLONAL ANTIBODIES TO RESPIRATORY SYNCYTIAL VIRUS Public/Granted day:2012-04-12
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