Invention Grant
US08221772B2 Pulmonary surfactant formulations and methods for promoting mucus clearance
有权
肺表面活性剂配方和促进粘液清除的方法
- Patent Title: Pulmonary surfactant formulations and methods for promoting mucus clearance
- Patent Title (中): 肺表面活性剂配方和促进粘液清除的方法
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Application No.: US11901866Application Date: 2007-09-19
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Publication No.: US08221772B2Publication Date: 2012-07-17
- Inventor: Mark. E. Johnson , Robert Segal , Thomas Hofmann , Robert J. Capetola
- Applicant: Mark. E. Johnson , Robert Segal , Thomas Hofmann , Robert J. Capetola
- Applicant Address: US PA Warrington
- Assignee: Discovery Laboratories Inc.
- Current Assignee: Discovery Laboratories Inc.
- Current Assignee Address: US PA Warrington
- Agency: Potter Anderson & Corroon LLP
- Main IPC: A61K9/12
- IPC: A61K9/12 ; A61K38/03 ; A61K38/16

Abstract:
Methods and compositions to enhance mucus clearance and to treat pulmonary lung disorders such as cystic fibrosis are disclosed. The methods utilize compositions including synthetic pulmonary surfactants having one or more phospholipids and a synthetic polypeptide, administered alone or combined with hyperosmotic agents, to patients in an amount effective to enhance mucus clearance.
Public/Granted literature
- US20080199410A1 Pulmonary surfactant formulations and methods for promoting mucus clearance Public/Granted day:2008-08-21
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