Invention Grant
US08221779B2 Compositions and methods for the delivery of poorly water soluble drugs and methods of treatment
有权
用于递送水溶性差的药物的组合物和方法以及治疗方法
- Patent Title: Compositions and methods for the delivery of poorly water soluble drugs and methods of treatment
- Patent Title (中): 用于递送水溶性差的药物的组合物和方法以及治疗方法
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Application No.: US12394833Application Date: 2009-02-27
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Publication No.: US08221779B2Publication Date: 2012-07-17
- Inventor: Jeffrey M. Jonas , Roger A. Rajewski , Bala Subramaniam , Katherine F. Terranova
- Applicant: Jeffrey M. Jonas , Roger A. Rajewski , Bala Subramaniam , Katherine F. Terranova
- Assignee: CritiTech, Inc.
- Current Assignee: CritiTech, Inc.
- Agency: Innovar, L.L.C.
- Agent Rick Matos
- Main IPC: A61F2/02
- IPC: A61F2/02
Abstract:
The present embodiment of the invention is generally directed to compositions comprising suspensions of poorly water-soluble compounds recrystallized in nanoparticulate sizes ranging from 0.1 to 5 μm. In addition, the embodiment of the invention is directed to methods for preparation and administration of these compositions to a patient for prevention and treatment of disease states. In particular, the embodiment of the invention is directed to compositions comprising suspensions of poorly water-soluble compounds, such as antimitotics and antibiotics, in nanoparticulates and methods of prevention and treatment of chronic disease states, such as cancer, by intraperitoneal and intravenous administration of such compositions.
Public/Granted literature
- US20090197821A1 COMPOSITIONS AND METHODS FOR THE DELIVERY OF POORLY WATER SOLUBLE DRUGS AND METHODS OF TREATMENT Public/Granted day:2009-08-06
Information query
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