Invention Grant
US08221988B2 Methods and compositions relating to CCR5 antagonist, IFN-γ and IL-13 induced inflammation
有权
与CCR5拮抗剂，IFN-γ和IL-13相关的方法和组合物诱导炎症
- Patent Title: Methods and compositions relating to CCR5 antagonist, IFN-γ and IL-13 induced inflammation
- Patent Title (中): 与CCR5拮抗剂，IFN-γ和IL-13相关的方法和组合物诱导炎症
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Application No.: US13084239Application Date: 2011-04-11
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Publication No.: US08221988B2Publication Date: 2012-07-17
- Inventor: Bing Ma , Jack Elias
- Applicant: Bing Ma , Jack Elias
- Applicant Address: US CT New Haven
- Assignee: Yale University
- Current Assignee: Yale University
- Current Assignee Address: US CT New Haven
- Agency: Morgan, Lewis & Bockius LLP
- Main IPC: G01N33/53
- IPC: G01N33/53 ; A61K39/395
Abstract:
The present invention includes compositions and methods for the treatment of Th1 and/or Th2 mediated inflammatory diseases, relating to inhibiting CCR5. This is because the present invention demonstrates, for the first time, that expression of IFN-γ, IL-13, and CCR5, mediates and/or is associated with Th1 and/or Th2 inflammatory diseases and that inhibiting CCR5 treats, and even prevents, the diseases. Thus, the invention relates to the novel discovery that inhibiting CCR5 treats and prevents Th1 and/or Th2 mediated inflammatory disease.
Public/Granted literature
- US20110311560A1 Methods and Compositions Relating to CCR5 Antagonist, IFN-Gamma and IL-13 Induced Inflammation Public/Granted day:2011-12-22
Information query
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