Invention Grant
US08222002B2 Human anti-amyloid beta peptide antibody and fragment of said antibody
有权
人抗淀粉样蛋白β肽抗体和所述抗体的片段
- Patent Title: Human anti-amyloid beta peptide antibody and fragment of said antibody
- Patent Title (中): 人抗淀粉样蛋白β肽抗体和所述抗体的片段
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Application No.: US12792064Application Date: 2010-06-02
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Publication No.: US08222002B2Publication Date: 2012-07-17
- Inventor: Kazuhisa Sugimura , Toshihiro Nakashima
- Applicant: Kazuhisa Sugimura , Toshihiro Nakashima
- Applicant Address: JP Kumamoto-shi
- Assignee: Juridical Foundation The Chemo-Sero-Therapeuric Research Institute
- Current Assignee: Juridical Foundation The Chemo-Sero-Therapeuric Research Institute
- Current Assignee Address: JP Kumamoto-shi
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2004-131839 20040427; JP2004-300590 20041014; JP2004-343945 20041129
- Main IPC: C12P21/02
- IPC: C12P21/02 ; C12N5/10 ; C12N15/00 ; C12N15/13 ; C07H21/04
Abstract:
A human anti-amyloid β peptide (hereinafter referred to as “Aβ”) antibody that binds to Aβ to thereby inhibit aggregation of Aβ molecules, and a fragment of said antibody are provided. The antibody and a fragment thereof according to the present invention, comprising a variable region of a human-derived anti-Aβ antibody, strongly reacts with Aβ to thereby inhibit its aggregation and hence may be used as a medicament for the prophylaxis and treatment of Alzheimer dementia.
Public/Granted literature
- US20100267816A1 HUMAN ANTI-AMYLOID BETA PEPTIDE ANTIBODY AND FRAGMENT OF SAID ANTIBODY Public/Granted day:2010-10-21
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