Invention Grant
- Patent Title: Methods for characterizing glycoproteins and generating antibodies for same
- Patent Title (中): 表征糖蛋白并产生相同抗体的方法
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Application No.: US13007393Application Date: 2011-01-14
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Publication No.: US08222208B2Publication Date: 2012-07-17
- Inventor: Dan Martin , Bernd Wollscheid , Rudolf H. Aebersold , Julian Watts
- Applicant: Dan Martin , Bernd Wollscheid , Rudolf H. Aebersold , Julian Watts
- Applicant Address: US WA Seattle
- Assignee: Institute for Systems Biology
- Current Assignee: Institute for Systems Biology
- Current Assignee Address: US WA Seattle
- Agency: Morrison & Foerster LLP
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C07K14/00
Abstract:
The invention provides methods for preparing a peptide as an immunogen to generate an antibody specific for the deglycosylated form of a glycopolypeptide by preparing a peptide that includes an N-linked glycosylation site of said glycopolypeptide and identifying a peptide sequence that includes said glycosylated site and preparing said peptide wherein N of said site is converted to D.
Public/Granted literature
- US20110230640A1 METHODS FOR CHARACTERIZING GLYCOPROTEINS AND GENERATING ANTIBODIES FOR SAME Public/Granted day:2011-09-22
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