Invention Grant
US08222216B2 Mesenchymal cell proliferation promoter and skeletal system biomaterial
有权
间充质细胞增殖启动子和骨骼系统生物材料
- Patent Title: Mesenchymal cell proliferation promoter and skeletal system biomaterial
- Patent Title (中): 间充质细胞增殖启动子和骨骼系统生物材料
-
Application No.: US12310577Application Date: 2007-08-29
-
Publication No.: US08222216B2Publication Date: 2012-07-17
- Inventor: Yoshinosuke Hamada , Nariaki Matsuura , Hiroshi Egusa , Yoshitoshi Kaneda , Masayuki Okazaki
- Applicant: Yoshinosuke Hamada , Nariaki Matsuura , Hiroshi Egusa , Yoshitoshi Kaneda , Masayuki Okazaki
- Applicant Address: JP Suita-Shi JP Higashi-Hiroshima-Shi
- Assignee: Osaka University,Hiroshima University
- Current Assignee: Osaka University,Hiroshima University
- Current Assignee Address: JP Suita-Shi JP Higashi-Hiroshima-Shi
- Agency: Edwards Wildman Palmer LLP
- Agent David G. Conlin; Elizabeth Spar
- Priority: JP2006-236970 20060831
- International Application: PCT/JP2007/066756 WO 20070829
- International Announcement: WO2008/026634 WO 20080306
- Main IPC: A61K38/08
- IPC: A61K38/08 ; C07K7/06
Abstract:
It is found that a SVVYGLR peptide (SEQ ID NO: 1) can promote proliferation of mesenchymal cells such as marrow-derived mesenchymal stem cells and dental pulp cells. A carbonate apatite-collagen sponge containing the SVVYGLR peptide (SEQ ID NO: 1) is useful as a biomaterial for the regeneration of bone marrow or dental pulp. It becomes possible to provide a skeletal system biomaterial which is capable of promoting the proliferation of the mesenchymal cells and is useful as artificial bone marrow or artificial dental pulp for repairing a defect in a bone marrow tissue or a dental pulp tissue.
Public/Granted literature
- US20110245187A1 MESENCHYMAL CELL PROLIFERATION PROMOTER AND SKELETAL SYSTEM BIOMATERIAL Public/Granted day:2011-10-06
Information query
IPC分类:
