Invention Grant
US08222217B2 Unacylated ghrelin as therapeutic agent in the treatment of metabolic disorders
有权
未经酰化的生长素释放肽作为治疗代谢紊乱的治疗剂
- Patent Title: Unacylated ghrelin as therapeutic agent in the treatment of metabolic disorders
- Patent Title (中): 未经酰化的生长素释放肽作为治疗代谢紊乱的治疗剂
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Application No.: US12130615Application Date: 2008-05-30
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Publication No.: US08222217B2Publication Date: 2012-07-17
- Inventor: Ezio Ghigo , Riccarda Granata , Aart Jan Van Der Lely
- Applicant: Ezio Ghigo , Riccarda Granata , Aart Jan Van Der Lely
- Applicant Address: FR Ecully
- Assignee: Alize Pharma SAS
- Current Assignee: Alize Pharma SAS
- Current Assignee Address: FR Ecully
- Agency: Fish & Richardson P.C.
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/08 ; A61K38/12 ; A61P3/10
Abstract:
An isolated polypeptide comprising any amino acid fragment of unacylated ghrelin or any analog thereof, wherein the polypeptide has an activity selected from the group consisting of a) decreasing blood glucose levels; b) increasing insulin secretion an/or sensitivity; c) binding to insulin-secreting cells; and d) promoting survival of insulin-secreting cells. As well as the use of the polypeptide in the treatment of a disorder associated with impaired glucose metabolism.
Public/Granted literature
- US20080312133A1 UNACYLATED GHRELIN AS THERAPEUTIC AGENT IN THE TREATMENT OF METABOLIC DISORDERS Public/Granted day:2008-12-18
Information query
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