Invention Grant
US08222226B2 Cell-type specific aptamer-siRNA delivery system for HIV-1 therapy
有权
用于HIV-1治疗的细胞型特异性适体 - siRNA递送系统
- Patent Title: Cell-type specific aptamer-siRNA delivery system for HIV-1 therapy
- Patent Title (中): 用于HIV-1治疗的细胞型特异性适体 - siRNA递送系统
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Application No.: US13108136Application Date: 2011-05-16
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Publication No.: US08222226B2Publication Date: 2012-07-17
- Inventor: John J. Rossi , Jiehua Zhou
- Applicant: John J. Rossi , Jiehua Zhou
- Applicant Address: US CA Duarte
- Assignee: City of Hope
- Current Assignee: City of Hope
- Current Assignee Address: US CA Duarte
- Agency: Rothwell, Figg, Ernst & Manbeck PC
- Main IPC: C12N15/11
- IPC: C12N15/11 ; C07H21/04
Abstract:
The present invention relates to compositions and methods for delivery of siRNA to specific cells or tissue. More particularly, the present invention relates to compositions and methods for cell type-specific delivery of anti-HIV siRNAs via fusion to an anti-gp120 aptamer.
Public/Granted literature
- US20110217769A1 CELL-TYPE SPECIFIC APTAMER-siRNA DELIVERY SYSTEM FOR HIV-1 THERAPY Public/Granted day:2011-09-08
Information query
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