Invention Grant
- Patent Title: Pharmaceutical compositions with superior product performance and patient compliance
- Patent Title (中): 具有卓越产品性能和患者依从性的药物组合物
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Application No.: US12689004Application Date: 2010-01-18
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Publication No.: US08222230B2Publication Date: 2012-07-17
- Inventor: Ashish Chatterji , Dipen Desai , Harpreet Sandhu , Navnit Hargovindas Shah
- Applicant: Ashish Chatterji , Dipen Desai , Harpreet Sandhu , Navnit Hargovindas Shah
- Applicant Address: US NJ Nutley
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Agent George W. Johnston; Patricia S. Rocha-Tramaloni; Kimberly J. Prior
- Main IPC: A01N43/04
- IPC: A01N43/04 ; A61K31/70
Abstract:
The present invention provides novel formulations of isobutyric acid (2R,3R,4R,5R)-5-(4-amino-2-oxo-2H-pyrimidin-1-yl)-4-fluoro-2-isobutyryloxymethyl-4-methyl-tetrahydro-furan-3-yl ester) and hydroxypropylcellulose that provide high bulk density, low particle size better suited for improved compression and flow, good compression, and fast dissolution profiles.
Public/Granted literature
- US20100184716A1 PHARMACEUTICAL COMPOSITIONS WITH SUPERIOR PRODUCT PERFORMANCE AND PATIENT COMPLIANCE Public/Granted day:2010-07-22
Information query
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