Invention Grant
US08222260B2 Substituted 6-anilinopurine derivatives as inhibitors of cytokinin oxidase/dehydrogenase and preparations containing these derivatives
有权
取代的6-苯胺嘌呤衍生物作为细胞分裂素氧化酶/脱氢酶的抑制剂和含有这些衍生物的制剂
- Patent Title: Substituted 6-anilinopurine derivatives as inhibitors of cytokinin oxidase/dehydrogenase and preparations containing these derivatives
- Patent Title (中): 取代的6-苯胺嘌呤衍生物作为细胞分裂素氧化酶/脱氢酶的抑制剂和含有这些衍生物的制剂
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Application No.: US12666189Application Date: 2008-07-02
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Publication No.: US08222260B2Publication Date: 2012-07-17
- Inventor: Lukas Spichal , Marketa Gemrotova , Marek Zatloukal , Jitka Frebortova , Petr Galuszka , Tomas Werner , Thomas Schmulling , Karel Dolezal , Miroslav Strnad
- Applicant: Lukas Spichal , Marketa Gemrotova , Marek Zatloukal , Jitka Frebortova , Petr Galuszka , Tomas Werner , Thomas Schmulling , Karel Dolezal , Miroslav Strnad
- Applicant Address: CZ Olomouc DE Berlin
- Assignee: Univerzita Palackego V Olomouci,Freie Universitat Berlin
- Current Assignee: Univerzita Palackego V Olomouci,Freie Universitat Berlin
- Current Assignee Address: CZ Olomouc DE Berlin
- Agency: Notaro, Michalos & Zaccaria P.C.
- Priority: CZPV2007-453 20070704
- International Application: PCT/CZ2008/000074 WO 20080702
- International Announcement: WO2009/003428 WO 20090108
- Main IPC: A61K31/52
- IPC: A61K31/52 ; C07D473/00
Abstract:
The invention relates to substituted 6-anilinopurine derivatives of the general formula I, wherein R denotes one to five substituents independently selected from the group consisting of hydrogen, halogen, hydroxyl, amino, alkyloxy and alkyl group, and R2 denotes amino, halogen, nitro, thio, alkylthio or alkyl group for use as inhibitors of cytokinin oxidase/dehydrogenase. The invention also relates to the compositions containing these derivatives.
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