Invention Grant
US08222266B2 Azabicyclo [3.1.0] hexyl derivatives as modulators of dopamine D3 receptors
失效
氮杂双环[3.1.0]己基衍生物作为多巴胺D3受体的调节剂
- Patent Title: Azabicyclo [3.1.0] hexyl derivatives as modulators of dopamine D3 receptors
- Patent Title (中): 氮杂双环[3.1.0]己基衍生物作为多巴胺D3受体的调节剂
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Application No.: US12295304Application Date: 2007-03-30
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Publication No.: US08222266B2Publication Date: 2012-07-17
- Inventor: Barbara Bertani , Anna Checchia , Romano Di Fabio , Gabriella Gentile , Fabrizio Micheli , Alessandra Pasquarello , Silvia Terreni
- Applicant: Barbara Bertani , Anna Checchia , Romano Di Fabio , Gabriella Gentile , Fabrizio Micheli , Alessandra Pasquarello , Silvia Terreni
- Applicant Address: GB Greenford, Middlesex
- Assignee: Glaxo Group Limited
- Current Assignee: Glaxo Group Limited
- Current Assignee Address: GB Greenford, Middlesex
- Agent Bonnie L. Deppenbrock
- Priority: GB0607892.7 20060403; GB0703397.0 20070221
- International Application: PCT/EP2007/053117 WO 20070330
- International Announcement: WO2007/113260 WO 20071011
- Main IPC: C07D403/06
- IPC: C07D403/06 ; A61K31/513
![Azabicyclo [3.1.0] hexyl derivatives as modulators of dopamine D3 receptors](/abs-image/US/2012/07/17/US08222266B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to certain azabicyclo compounds of formula (I)′: wherein the various groups are defined herein and that are modulators of dopamine D3 receptors, e.g. to treat drug dependency, as antipsychotic agents, to treat obsessive compulsive spectrum disorders, or premature ejaculation.
Public/Granted literature
- US20100069416A1 Azabicyclo [3.1.0] Hexyl Derivatives as Modulators of Dopamine D3 Receptors Public/Granted day:2010-03-18
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