Invention Grant
- Patent Title: Tyrosine kinase inhibitors
- Patent Title (中): 酪氨酸激酶抑制剂
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Application No.: US12309149Application Date: 2007-07-06
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Publication No.: US08222269B2Publication Date: 2012-07-17
- Inventor: Christopher J. Dinsmore , Matthew H. Katcher , Alan B. Northrup
- Applicant: Christopher J. Dinsmore , Matthew H. Katcher , Alan B. Northrup
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent David A. Muthard
- International Application: PCT/US2007/015675 WO 20070706
- International Announcement: WO2008/008310 WO 20080117
- Main IPC: A61K31/55
- IPC: A61K31/55 ; C07D221/06
Abstract:
The present invention relates to 5H-benzo[4,5]cyclohepta[1,2-b]pyridine derivatives of formula (I) that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
Public/Granted literature
- US20090203684A1 Tyrosine kinase inhibitors Public/Granted day:2009-08-13
Information query
