Invention Grant
US08222287B2 Substituted anthra[1,2-D]imidazolediones and pharmaceutical utility thereof
有权
取代的蒽[1,2-D]咪唑啉酮及其药用效用
- Patent Title: Substituted anthra[1,2-D]imidazolediones and pharmaceutical utility thereof
- Patent Title (中): 取代的蒽[1,2-D]咪唑啉酮及其药用效用
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Application No.: US12749253Application Date: 2010-03-29
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Publication No.: US08222287B2Publication Date: 2012-07-17
- Inventor: Hsu-Shan Huang
- Applicant: Hsu-Shan Huang
- Applicant Address: TW Taipei
- Assignee: National Defense Medical Center
- Current Assignee: National Defense Medical Center
- Current Assignee Address: TW Taipei
- Agency: Volpe and Koenig, P.C.
- Priority: TW97112087A 20080402
- Main IPC: A61K31/415
- IPC: A61K31/415
![Substituted anthra[1,2-D]imidazolediones and pharmaceutical utility thereof](/abs-image/US/2012/07/17/US08222287B2/abs.jpg.150x150.jpg)
Abstract:
A heteroannelated anthraquinone derivative compound is provided. The heteroannelated anthraquinone derivative compound is represented by a formula (I): wherein R1 is a substituent being one selected from a group consisting of i) a first substituent being one selected from a group consisting of a hydryl group, an amino group, a nitro group, a hydroxyl group and a cyan group, ii) a second substituent being one selected from a group consisting of (CH2)nX, a straight (CH2)n alkyl group, a (CH2)n alkoxyl group, a branched (CH2)n alkyl group, a C3˜C12 nephthenic group, and a C3˜C12 cyclic alkoxyl group, wherein 1≦n≦12, and X is a halogen, iii) a third substituent being one selected from a group consisting of a straight C1˜C8 alkyl group with a double-bond, a C1˜C8 alkoxyl group with a double-bond, a branched C1˜C8 alkyl group with a double-bond and a C3˜C8 nephthenic group with a double-bond, and iv) a fourth substituent of a C5˜C12 heterocyclic group.
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