Invention Grant
US08222456B2 Facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers and uses thereof
有权
表面两亲性聚芳基和聚芳基炔基聚合物和低聚物及其用途
- Patent Title: Facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers and uses thereof
- Patent Title (中): 表面两亲性聚芳基和聚芳基炔基聚合物和低聚物及其用途
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Application No.: US11038787Application Date: 2005-01-21
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Publication No.: US08222456B2Publication Date: 2012-07-17
- Inventor: William F. DeGrado , Dahui Liu , Gregory N. Tew , Michael L. Klein
- Applicant: William F. DeGrado , Dahui Liu , Gregory N. Tew , Michael L. Klein
- Applicant Address: US PA Philadelphia
- Assignee: The Trustees of the University of Pennsylvania
- Current Assignee: The Trustees of the University of Pennsylvania
- Current Assignee Address: US PA Philadelphia
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Main IPC: C07C211/27
- IPC: C07C211/27 ; C07C279/06 ; C07C233/77 ; A61K31/135 ; A61K31/155 ; A61K31/16 ; A61K31/132
Abstract:
The present invention discloses methods of use of facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers, including, but not limited to, pharmaceutical uses of the polymers and oligomers as antimicrobial agents and as antidotes for hemorrhagic complications associated with heparin therapy. The present invention also discloses novel facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers, compositions of the novel polymers and oligomers, including pharmaceutical compositions, and methods of designing and synthesizing the facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers.
Public/Granted literature
- US20050287108A1 Facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers and uses thereof Public/Granted day:2005-12-29
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