A pixel array structure, a flat display panel and a method for driving a flat display panel thereof are provided. The structure of the pixel array structure and the flat display panel is the structure of the half source driving (HSD). Therefore, by skillfully arranging the coupled relationship between each pixel and each data line, the pixel array structure provided in the present invention can be driven by the gate driver directly disposed on the substrate of the pixel array. Accordingly, not only the fabrication cost of the flat display panel can be reduced, but the manner of the timing controller controlling the gate driver and source driver can also be reduced.