When a mobile telephony device is conducting a voice over Internet protocol (VOIP) telephone call via a data network, and the mobile telephone device transitions from a first wireless data connection to a second wireless data connection, signaling between the mobile telephone device and a media relay inform the media relay how to address data packets bearing the media of the call after the transition has occurred. In some embodiments, the mobile telephone device establishes multiple simultaneous wireless data connections, and the mobile telephony device switches the media of the call between the wireless data connections depending on the quality of the wireless data connections.