In one example, a method of examining a container is disclosed comprising detecting a potential threat within contents of a container using radiation scanning and disabling the potential threat with radiation. In another example, a method of examining a container is disclosed comprising scanning at least a portion of the container with a first radiation beam, detecting radiation interacting with contents of the container, identifying a potential threat contained based, at least in part, on the detected radiation, and disabling the potential threat with a dose of radiation from a second radiation beam. The potential threat may be a nuclear, chemical, and/or biological weapon, for example. Chemical and/or biological detectors may also be provided. The threat and/or electronics associated with the threat, may be disabled. Systems are also disclosed.