A control strategy for heating, ventilating, and air-conditioning (HVAC) units used to condition the environment in data centers and other commercial buildings such as retail stores with an open-plan design is provided to coordinate the operation of the actuators of the HVAC units. A supervisory controller receives feedback signals from a plurality of environmental sensors and uses a set of references values to determine control signals to the actuators of the HVAC units. A pseudoinverse of a transfer function matrix G may be used to determine the control signals from errors in the feedback signals relative to the reference signals.