A method and system for power supply management in an integrated chip selectively manages the power supplied to the various circuits within the integrated circuit. The integrated circuit includes a combinational logic block, a memory block, a power supply block, and a control block. The power supply block includes multiple power regulators for generating power supply potentials of various magnitudes. The control block receives a power down signal, a clock disable signal, and a temperature threshold signal, and generates control signals for controlling the magnitude of the potential of the power supplied to the combinational logic block and the memory block by the power supply block.